Maria Lucia Valentino Selected Research

Thymidine Phosphorylase

10/2008

Gastrointestinal dysmotility in mitochondrial neurogastrointestinal encephalomyopathy is caused by mitochondrial DNA depletion.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Maria Lucia Valentino Research Topics

Disease

18	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 01/2023 - 06/2002
13	Mitochondrial Diseases (Mitochondrial Disease) 10/2022 - 10/2008
7	Optic Nerve Diseases (Optic Neuropathy) 01/2017 - 02/2008
7	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2017 - 11/2004
5	Optic Atrophy 01/2020 - 02/2008
4	Mitochondrial Myopathies (Mitochondrial Myopathy) 12/2020 - 02/2008
4	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 01/2018 - 02/2008
4	Deafness (Deaf Mutism) 07/2015 - 02/2008
3	Stroke (Strokes) 10/2020 - 05/2009
3	Lactic Acidosis 10/2020 - 05/2009
3	MELAS Syndrome (Syndrome, MELAS) 10/2020 - 05/2009
3	Atrophy 01/2012 - 03/2006
2	Migraine Disorders (Migraine) 10/2022 - 05/2013
2	Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy) 01/2022 - 10/2020
2	Ganglion Cysts (Ganglion) 01/2022 - 09/2014
2	MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers) 01/2022 - 05/2013
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2022 - 10/2020
2	Muscle Weakness 01/2022 - 05/2013
2	Deglutition Disorders (Dysphagia) 10/2021 - 08/2014
2	Wolfram Syndrome (Syndrome, Wolfram) 06/2020 - 01/2020
2	Muscular Diseases (Myopathy) 01/2019 - 08/2014
2	Parkinsonian Disorders (Parkinsonism) 01/2018 - 07/2015
2	Hearing Loss (Hearing Impairment) 01/2016 - 05/2013
2	Cognitive Dysfunction 07/2015 - 05/2013
2	Cataract (Cataracts) 08/2014 - 05/2009
2	Ataxia (Dyssynergia) 05/2013 - 02/2008
2	Friedreich Ataxia (Friedreich's Ataxia) 05/2009 - 01/2009
2	Intestinal Pseudo-Obstruction (Intestinal Pseudoobstruction) 10/2008 - 03/2006
1	Muscular Dystrophies (Muscular Dystrophy) 02/2024
1	Starvation 10/2023
1	Headache (Headaches) 10/2022
1	Myofibrillar Myopathy 12/2021
1	Inclusion Body Myositis 10/2021
1	COVID-19 01/2021
1	Fatigue 12/2020
1	Pain (Aches) 12/2020
1	Status Epilepticus (Complex Partial Status Epilepticus) 10/2020
1	Macular Degeneration (Age-Related Maculopathy) 01/2020
1	Renal Insufficiency (Renal Failure) 01/2020
1	Cytochrome-c Oxidase Deficiency 01/2018
1	Corticobasal Degeneration 01/2017
1	Peripheral Nervous System Diseases (PNS Diseases) 07/2015
1	Dementia (Dementias) 07/2015
1	CADASIL 06/2015
1	Kearns-Sayre Syndrome 05/2015
1	VLCAD deficiency 05/2015
1	Auditory neuropathy 03/2015
1	Mitochondrial encephalopathy 03/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2013
1	Myalgia 05/2013
1	Cardiomyopathies (Cardiomyopathy) 05/2013
1	Myoclonus (Nocturnal Myoclonus) 05/2013
1	Ophthalmoplegia (External Ophthalmoplegia) 05/2013
1	Seizures (Absence Seizure) 05/2013
1	Tremor (Tremors) 05/2013
1	Lipoma (Lipomata) 05/2013
1	Brain Diseases (Brain Disorder) 01/2013
1	Hereditary Spastic Paraplegia 05/2009

Drug/Important Bio-Agent (IBA)

32	Mitochondrial DNA (mtDNA)IBA 01/2023 - 02/2002
9	Retinaldehyde (Retinal)IBA 01/2022 - 01/2005
4	Mitochondrial Proteins (Mitochondrial Protein)IBA 05/2011 - 11/2004
4	Adenosine Triphosphate (ATP)IBA 05/2011 - 02/2002
3	Lactic Acid (Lactate)FDA LinkGeneric 10/2022 - 05/2011
2	Amino Acids FDA Link 10/2023 - 11/2004
2	fibroblast growth factor 21IBA 12/2020 - 10/2020
2	Biomarkers (Surrogate Marker)IBA 12/2020 - 10/2020
2	Creatine Kinase (Creatine Phosphokinase)IBA 12/2020 - 05/2013
2	CalciumIBA 06/2020 - 01/2020
2	idebenoneIBA 02/2013 - 09/2011
2	Phosphorus (Red Phosphorus)IBA 05/2011 - 01/2011
2	GTP Phosphohydrolases (GTPases)IBA 02/2008 - 11/2004
2	Dynamins (Dynamin)IBA 02/2008 - 11/2004
1	RNA (Ribonucleic Acid)IBA 02/2024
1	AcidsIBA 10/2022
1	Analgesics (Analgesic Drugs)IBA 10/2022
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Lys Transfer RNAIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 12/2021
1	AutoantibodiesIBA 10/2021
1	AntibodiesIBA 10/2021
1	GlucocorticoidsIBA 01/2021
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2021
1	Transfer RNA (tRNA)IBA 10/2020
1	Growth Differentiation Factor 15IBA 10/2020
1	CeroidIBA 01/2017
1	ProgranulinsIBA 01/2017
1	LipofuscinIBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	Notch ReceptorsIBA 06/2015
1	Cytochromes b (Cytochrome b)IBA 08/2014
1	Estrogens (Estrogen)FDA Link 03/2014
1	Calcium Channels (Calcium Channel)IBA 01/2013
1	Carisoprodol (Soma)FDA LinkGeneric 01/2012
1	Glutamic Acid (Glutamate)FDA Link 05/2009

Therapy/Procedure

3	Therapeutics 01/2022 - 10/2020
2	Lasers (Laser) 01/2018 - 02/2014
1	Transplantation 01/2020
1	Cochlear Implantation 03/2015